ADPKD vs ARPKD: What’s the Difference?

Autosomal dominant (ADPKD) is one of the most common life-threatening genetic diseases. ADPKD affects approximately 1 in 500. It does not skip a generation. There is usually a family history of ADPKD. Parents with ADPKD have a 50 percent chance of passing the disease on to each of their children.

Autosomal recessive (ARPKD) is a relatively rare genetic disorder, occurring in approximately 1 in 20,000 individuals. It affects boys and girls equally and often causes significant mortality in the first month of life.